Drug Use Evaluation on Ceftazidime

Kim, Sang Hyun; Choi, Hyun Suk; Kim, Hyang Suk; Shin, Wan Gyoon; Shon, In Ja; Cho, Nam Chun; Choi, Kang Won

Journal of Korean Society Quality Assurance Health Care 1994;1(1): 44.
Published online May 30, 1994.

입원환자에 대한 Ceftazidime의 약물사용 검토

김상현¹, 최현숙¹, 김향숙¹, 신완균¹, 손인자¹, 조남춘¹, 최강원²

¹서울대학교병원 약제부
²서울대학교병원 내과

Drug Use Evaluation on Ceftazidime

Sang Hyun Kim¹, Hyun Suk Choi¹, Hyang Suk Kim¹, Wan Gyoon Shin¹, In Ja Shon¹, Nam Chun Cho¹, Kang Won Choi²

¹Dept. of Pharmacy
²Dept. of Internal Medicine

Abstract

A drug use evaluation (DUE) program has been defined as an "authorized a quality assurance process designed to ensure that drugs are used appropriately, safely, and effectively". A retrospective DUE study on ceftazidime has been conducted by reviewing patients charts following criteria for drug use evaluation established by Am.S.Hosp.Pharm. Total 60 charts of patient treated with ceftazidime in Seoul National University Hospital from Jan. 1.1993 to July.31.1993 were retrospectively reviewed. As a result, 44 cases(73%) were met with the criteria for the justification of use. In analysing process indicators including culture and sensitivity test, CBC, LFT, history of anaphylaxis monitoring before initial dose, vital sign monitoring were relatively well documented showing the accepted level above 80%, while appropriated dose were infrequently documented with low accepted level. In outcome analysis, blood culture after discontinuing drug were rarely documented, with accepted level of 46%. For using effectively and safely, ceftazidime is recommended to be administrated to optimal indication, and monitored actively for preventing adverse effect.

Key words Ceftazidime;Drug Use Evaluation;Justification of use;Pseudomonas aeruginosa;