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Journal of Korean Society Quality Assurance Health Care 2006;12(1): 52.
Published online May 30, 2006.
우리나라 일부 의학 학술지에 게재된 의약품 광고의 과학적 근거에 대한 평가
안성복1, 최원2, 김철준2, 최성준3, 이강희4, 하경수1, 김현창1
1연세대학교 의과대학 예방의학교실
2한국 엠에스디 의학부
3사노피 신데라보 코리아 의학부
4보건복지부 국제협력팀
Quality of the pharmaceutical advertisement claims in five medical journals in Korea
Song Vogue Ahn1, Won Choi2, Chul Joon Kim2, Seong Choon Choe3, Kang Hee Lee4, Kyoungsoo Ha1, Hyeon Chang Kim1
1Department of Preventive Medicine, Yonsei University College of Medicine
2Medical Department, MSD Korea
3Medical Department, Sanofi-Synthelabo Korea
4International Cooperation Team, Ministry of Health and Welfare
The promotion and advertisement of pharmaceuticals should be based on evidence from clinical trials. We conducted this study to assess whether the pharmaceutical advertisement claims in Korean medical journals had relevant references, and whether the claims were supported by the references.
We reviewed pharmaceutical advertisements in five Korean medical journals issued during the first half of 1999 and during the first half of 2004. Three investigators independently reviewed the advertisements to see whether the studies quoted to endorse the advertising messages supported the corresponding claims. Using multiple logistic regression analyses, we investigated which factors were associated with the quality of the advertisement claims.
From the 550 advertisements in the five journals, we identified 157 different advertisements and 475 different promotional claims. Only 149 claims had at least one reference, and 105 claims had references of published article. We could find supporting evidences in the 90 claims. The factors which were associated with the quality of advertisement claims were category of drugs, category of claims, and the manufacturer characteristics. Claims for cardiovascular and endocrine drugs, and claims on efficacy, and claims of multinational company were more evidence-based.
Majority of the pharmaceutical advertisement claims in Korea did not have appropriate references. Drug category, claim category, and the manufacturer characteristics were associated with the quality of advertisement claims, and the manufacturer characteristics was the most important determinants.
Key words Quality;Evidence;Pharmaceutical;


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